I-Pregabalin sisiyobisi esitsha sokulwa nesifo sokuwa, sinesakhiwo se-γ-amino butyric acid kwisakhiwo sayo seemolekyuli, ezineziphumo ze-anticonvulsant.
Igama lemveliso | IPregabalin |
CAS Hayi. | 148553-50-8 |
Ucoceko | 99% |
Ifomula yeMolekyuli | C8H17NO2 |
Ubunzima beMolekyuli | 159.23 |
Indawo yokunyibilika | Ngo-194-196 ° C. |
Ukuxinana | 0.997 ± 0.06 g / cm3 (Uqikelelo) |
Inkangeleko | Umgubo omhlophe wekristale |
IBakala | Ibanga lezamayeza |
Udidi | Isixhobo esisebenzayo seMithi (API) |
Iklasi yeziyobisi | I-Anticonvulsant -I-GABA Analogs · Iswekile ye-Peripheral Neuropathy Agents · I-Fibromyalgia Agents -I-GABA Analogs · Unyango lwe-Neuropathic Pain Therapy · I-Postherpetic Neuralgia Agents |
Igama lebrand | SHXLCHEM |
Inkcazo | Mhlophe ukucoca umgubo omhlophe wekristallini |
Ukuphendulwa kombala | Isisombululo sokuphendula seNinhydrin simbala oluhlaza okwesibhakabhaka |
Ukuchongwa kwe-IR | Umboniso we-IR uyahambelana nomgangatho wesalathiso |
Ukunyibilika | Ukunyibilika kancinci emanzini ngokungaboni |
Ujikelezo oluthile lwamehlo | Phakathi + kwe-8.5 ° ukuya kwi-12.0 ° |
Izinto ezinxulumene noko yi-HPLC (-) Amide | Hayi ngaphezulu kwe-0.15% |
4E | Hayi ngaphezulu kwe-0.15% |
5E | Hayi ngaphezulu kwe-0.15% |
Ilactum | Hayi ngaphezulu kwe-0.15% |
Ukungahlambuluki okungaziwayo | Hayi ngaphezulu kwe-0.15% |
Ukungahlambuluki okupheleleyo | Hayi ngaphezulu kwe-0.15% |
Isinyithi esinzima | Hayi ngaphezulu kwe-200ppm |
Uthuthu oluSulphated | Hayi ngaphezulu kwe-0.1% w / w |
Ukuphulukana nokomisa | Hayi ngaphezulu kwe-0.5% w / w |
Imethanol | Hayi ngaphezulu kwe-3000ppm |
Toluene | Hayi ngaphezulu kwe-890ppm |
I-N-butanol | Hayi ngaphezulu kwe-5000ppm |
Ethyl acetate | Hayi ngaphezulu kwe-5000ppm |
IChloroform | Hayi ngaphezulu kwe-60ppm |
I-N-hexane | Hayi ngaphezulu kwe-290ppm |
Ukucoceka kwe-Emantiomeric ngumxholo we-HPLC R-Pregabalin | Akukho ngaphezulu kwe-0.15% yendawo yeR-Pregabalin |
Uvavanyo olwenziwe yi-HPLC (kwisiseko esomileyo) | Ungabikho ngaphezulu kwe-98.0 w / w kwaye ungabi ngaphezulu kwe-102.0% w / w |
I-Pregabalin sisixhobo esisebenzayo seMithi (i-API), esihlala sisetyenziselwa ukubulala iintlungu ezibangelwa ngumonakalo wemithambo-luvo ngenxa yesifo seswekile, usulelo (herpes zoster) usulelo, okanye ukonzakala kwethambo lomqolo. I-Pregabalin ikwasetyenziselwa ukunyanga iintlungu kubantu abane-fibromyalgia. Kukwasetyenziswa kunye namanye amayeza ukunyanga iintlobo ezithile zokuthimba (ukugxilwa kugxile).
Ndingayithatha njani i-pregabalin?
Nxibelelana: erica@shxlchem.com
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