API Obeticholic acid CAS 459789-99-2 for biliary cholangitis Umfanekiso Featured

I-API Obeticholic acid CAS 459789-99-2 ye-biliary cholangitis

Inkcazelo emfutshane:

I-Obeticholic acid isetyenziswa yodwa okanye kunyango oludibeneyo lwesifo esithile sesibindi (primary biliary cholangitis-PBC).

Qhagamshelana: Erica Zheng

Email: erica@zhuoerchem.com

Umnxeba: +86 21 2097 0332

Ihlokondiba: +86 177 1767 9251

WhatsApp: +86 186 2503 6043 (WeChat & Telegram & Line)

Skype: slhyzy

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Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo

I-Obeticholic acid isetyenziswa yodwa okanye kunyango oludibeneyo lwesifo esithile sesibindi (primary biliary cholangitis-PBC).

Inkcazo:

Igama lemveliso	I-Obeticholic Acid
Igama leMchiza	6-Ethylchenodeoxycholic acid
Elinye Igama	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph4 Acid7,6(INT)(INT) -ECDCA)
Inombolo yeCAS	459789-99-2
Ifomula yeemolekyuli	C26H44O4
Ubunzima beFormula	420.63
Imbonakalo	Umgubo omhlophe
Isivavanyi	99.0% min
Ukuxinana	1.091 g/cm3
Indawo yokunyibilika	108-110 °C
Indawo yokubilisa	562.9±25.0 °C
Iphakheji	20kg/bag/drum, 25kg/bag/drum, okanye njengoko ubufuna
Ugcino	Gcina isikhongozeli sivalwe ngokuqinileyo kwindawo eyomileyo nepholileyo.Musa ukuveza ukukhanya kwelanga.
I-COA kunye ne-MSDS	Iyafumaneka

Ukusetyenziswa

I-Obeticholic acid yi-dihydroxy-5beta-cholanic acid eyi-chenodeoxycholic acid ephethe i-ethyl substituent eyongezelelweyo kwi-6alpha-position.I-semi-synthetic bile acid esebenza njenge-farnesoid X receptor agonist kwaye isetyenziselwa unyango lwe-primary biliary cholangitis.Inendima njenge-farnesoid X receptor agonist kunye ne-hepatoprotective agent.I-dihydroxy-5beta-cholanic acid, i-3alpha-hydroxy steroid kunye ne-7alpha-hydroxy steroid.Ivela kwi-asidi ye-chenodeoxycholic.
I-Obeticholic acid (OCA) i-synthetically modified bile acid kunye ne-agonist enamandla ye-farnesoid X i-nuclear receptor (FXR) esetyenziselwa ukunyanga izifo zesibindi ezibandakanya i-primary biliary cholangitis.